Monocyte-Derived Macrophages Are Impaired in Myelodysplastic Syndrome
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چکیده
منابع مشابه
Monocyte-Derived Macrophages Are Impaired in Myelodysplastic Syndrome
Background. The myelodysplastic syndrome (MDS) comprises a group of clonal hematopoietic stem cell diseases characterized by cytopenia, dysplasia in one or more of the major myeloid lineages, ineffective hematopoiesis, and increased risk of development of acute myeloid leukemia (AML). Macrophages are innate immune cells that ingest and degrade abnormal cells, debris, and foreign material and or...
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The present study was conducted to quantify and compare TLR2 (toll-like receptor 2) activity in monocyte-derived macrophages of zebu (Tharparkar) and crossbred (Holstein-Friesian × Jersey × Brown Swiss × Hariana) cattle. The cells were either induced with Pam3CSK4 or kept as control. The TLR2 activity was quantified in terms of IκB-α inhibitory subunit (NFKBIA) messenger RNA (mRNA) copies...
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ژورنال
عنوان ژورنال: Journal of Immunology Research
سال: 2016
ISSN: 2314-8861,2314-7156
DOI: 10.1155/2016/5479013